Weekly Supplement BS Report

September 14, 2009 by admin  
Filed under Weekly Supplement BS Report

Weekly Supplement BS Report

September 13th, 2009 Volume I Issue 2

CEE…BSN™s newest proprietary blend, designed to increase water and lipid solubility of creatine.
-product description of BSN Cellmass

Creatine Ethyl Ester (CEE) uses the ethyl ester to deliver the creatine into the bloodstream (and it does this very well)…
-product description of SizeOn

Creatine Ethyl Ester: Creatine ethyl ester is one of the newest forms of creatine. The ethyl ester prevents breakdown in the gut and prolongs the life of creatine in the blood. Combined with creatine monohydrate this results in a one-two punch of fast acting immediate action coupled with the longer duration of creatine ethyl ester. - CEE gives you a longer acting creatine, the right amount works, too much and it tastes like battery acid.
-product description of LG Science’s Cold Fusion EX

CEE…..This means, simply, that not only will dosage requirements be lower, but the absorption of esterified creatine will be increased and the infamous “creatine bloat” will be eliminated!
-product description of Higher Power Creatine Ethyl Ester

Creatine Ethyl Ester HCL is an exceptionally soluble creatine resulting in advanced absorption, increased bioavailability, and stability. Instead of saturating your system in creatine and hoping for absorption, creatine ethyl ester directly penetrates the muscle cell resulting in 30 to 40 times more functional creatine. This means no more loading, bloating, cramping or dehydration. Most users notice a difference in their first dose.
-product description Axis Labs’ Creatine Ethyl Ester

Myth: Creatine Ethyl Ester (CEE) is superior to creatine monohydrate. Not only does it cause less bloating, but because of its improved bioavailability you don’t need to take as much.
Fact: Not only does it taste like urine, but you’ll probably get the exact same results no matter which one you drink (CEE or urine).

The evidence:
It’s pretty easy to prove that a new creatine is superior to creatine monohydrate. All we would have to do is track the new creatine through our system. We’d first take a blood sample to ensure its absorption through the GI tract. Then we’d look at the creatine content within the muscle and make sure it actually does get more creatine inside the muscle. And if we’re really good, we’d set up a study that actually showed (with hard numbers) the superior results one would get with the new creatine product compared to the old one.
So that’s basically what I was looking for when I searched pubmed.org. And I found…
*Most pertinent statements are bolded.

The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels.
Mike Spillane, Ryan Schoch, Matt Cooke, Travis Harvey, Mike Greenwood, Richard Kreider and Darryn S Willoughby
J Int Soc Sports Nutr. 2009 Feb 19;6:6

ABSTRACT: Numerous creatine formulations have been developed primarily to maximize creatine absorption. Creatine ethyl ester is alleged to increase creatine bio-availability. This study examined how a seven-week supplementation regimen combined with resistance training affected body composition, muscle mass, muscle strength and power, serum and muscle creatine levels, and serum creatinine levels in 30 non-resistance-trained males. In a double-blind manner, participants were randomly assigned to a maltodextrose placebo (PLA), creatine monohydrate (CRT), or creatine ethyl ester (CEE) group. The supplements were orally ingested at a dose of 0.30 g/kg fat-free body mass (approximately 20 g/day) for five days followed by ingestion at 0.075 g/kg fat free mass (approximately 5 g/day) for 42 days. Results showed significantly higher serum creatine concentrations in PLA (p = 0.007) and CRT (p = 0.005) compared to CEE. Serum creatinine was greater in CEE compared to the PLA (p = 0.001) and CRT (p = 0.001) and increased at days 6, 27, and 48. Total muscle creatine content was significantly higher in CRT (p = 0.026) and CEE (p = 0.041) compared to PLA, with no differences between CRT and CEE. Significant changes over time were observed for body composition, body water, muscle strength and power variables, but no significant differences were observed between groups. In conclusion, when compared to creatine monohydrate, creatine ethyl ester was not as effective at increasing serum and muscle creatine levels or in improving body composition, muscle mass, strength, and power. Therefore, the improvements in these variables can most likely be attributed to the training protocol itself, rather than the supplementation regimen.

So this study suggested the following:
1) With CEE, you’ll get less creatine in the bloodstream than regular creatine monohydrate.
2) With CEE, you’ll get more creatinINe (a useless byproduct) in the bloodstream than regular creatine monohydrate. Remember this.
3) With CEE, it takes almost 27 days to increase the creatine content within the muscle, compared to just 6 days with creatine monohydrate.

So now we have we have to ask: What in the hell is happening to CEE once it enters the body because it’s not improving creatine’s bioavailability?

Non-enzymatic cyclization of creatine ethyl ester to creatinine.
Biochem Biophys Res Commun. 2009 Oct 16;388(2):252-5. Epub 2009 Aug 4
Giese MW, Lecher CS

Creatine ethyl ester was incubated at 37 degrees C in both water and phosphate-buffered saline and the diagnostic methylene resonances in the (1)H NMR spectrum were used to identify the resultant products. It was found that mild aqueous conditions result in the cyclization of creatine ethyl ester to provide inactive creatinine as the exclusive product, and this transformation becomes nearly instantaneous as the pH approaches 7.4. This study demonstrates that mild non-enzymatic conditions are sufficient for the cyclization of creatine ethyl ester into creatinine, and together with previous results obtained under enzymatic conditions suggests that there are no physiological conditions that would result in the production of creatine. It is concluded that creatine ethyl ester is a pronutrient for creatinine rather than creatine under all physiological conditions encountered during transit through the various tissues, thus no ergogenic effect is to be expected from supplementation.

Non-enzymatic hydrolysis of creatine ethyl ester.
Biochem Biophys Res Commun. 2009 Aug 21;386(2):363-7. Epub 2009 Jun 12
Katseres NS, Reading DW, Shayya L, Dicesare JC, Purser GH

The rate of the non-enzymatic hydrolysis of creatine ethyl ester (CEE) was studied at 37 degrees C over the pH range of 1.6-7.0 using (1)H NMR. The ester can be present in solution in three forms: the unprotonated form (CEE), the monoprotonated form (HCEE(+)), and the diprotonated form (H(2)CEE(2+)). The values of pK(a1) and pK(a2) of H(2)CEE(2+) were found to be 2.30 and 5.25, respectively. The rate law is found to be Rate=-dCCEE/dt=k++[H2CEE2+][OH-]+k+[HCEE+][OH-]+k0[CEE][OH-] where the rate constants k(++), k(+), and k(0) are (3.9+/-0.2)x10(6)L mol(-1)s(-1), (3.3+/-0.5)x10(4)L mol(-1)s(-1), and (4.9+/-0.3)x10(4)L mol(-1)s(-1), respectively. Calculations performed at the density functional theory level support the hypothesis that the similarity in the values of k(+) and k(0) results from intramolecular hydrogen bonding that plays a crucial role. This study indicates that the half-life of CEE in blood is on the order of one minute, suggesting that CEE may hydrolyze too quickly to reach muscle cells in its ester form.

Qualitative In vitro NMR Analysis of Creatine Ethyl Ester Pronutrient in Human Plasma.
Int J Sports Med. 2009 Jul 7.
Giese MW, Lecher CS.

There are a number of forms of creatine available that attempt to improve the solubility and permeability, with the anticipation this will result in an improved pharmacokinetic profile and ultimately an enhanced ergogenic response. Previous research has shown that the different salt forms can improve solubility resulting in slightly altered pharmacokinetic profiles, however specific data exploring the conversion of esterified derivatives to creatine is lacking. The purpose of this study was to examine the assertion that creatine ethyl ester undergoes enzymatic conversion to creatine in human tissues. The IN VITRO response of creatine ethyl ester to incubation in human plasma was examined by H-NMR analysis. Lyophilized human plasma was reconstituted in D (2)O and phosphate-buffered saline and 1.5 mg of the analyte was added. Following incubation at 37 degrees C for 4 h and subsequent protein precipitation, the supernatant was analyzed by NMR, utilizing the diagnostic chemical shift of the methylene signal to determine the species present in solution, I.E. creatine ethyl ester, creatine, or creatinine. Both creatine and creatinine were run in parallel as control experiments and each assay was run in triplicate. As expected both creatine and creatinine remained unchanged. However, conversion of creatine ethyl ester to creatine by the esterases in human plasma was not observed to any detectable extent and the only species detected after the incubation period was creatinine. While not a definitive characterization of the IN VIVO behavior, these results strongly warrant a complete IN VIVO pharmacokinetic analysis of creatine ethyl ester since it appears these “pronutrients” may actually provide large exogenous sources of pharmacologically inactive creatinine rather than ergogenic creatine.

Surprise. Surprise. It’s being converted to the useless byproduct creatiNINE, not creatine. So that’s why more creatinine is showing up in the blood, less creatine is showing up in the blood, and it’s taking longer to fill the muscle with creatine. Ah, the legitamacy of the dietary supplement industry. I can’t believe the efficacy studies prior to its release didn’t catch that. Oh wait, those aren’t required. Neither are safety studies.

Everyone together now…… B_LLSH_T

-Doc

The Weekly Supplement BS Report

September 10, 2009 by admin  
Filed under Weekly Supplement BS Report

The Weekly Supplement BS Report
September 10th, 2009 Volume I Issue 1

I read a lot. In fact, on average every month, I’ll read 3-4 fitness retail magazines, along with 2-3 fitness trade magazines, and usually a book or two that’s related to nutrition or strength training. I’m also an active member on 6 fitness message boards, as well as a subscriber to 7 fitness blogs. Did I also mention I spend usually an hour a day skimming through pubmed.org for new research articles? What can I say? I lead one boring life.

So why do I do it? Because supplements work, and some of them work extremely well. Not only have I seen it in the research, but I’ve personally experienced it as well as seen tremendous results from others. However, I’d be willing to bet that 80% of what I read is pure, unadulterated BS (closer to 95% if you just limit it to dietary supplements). To get to the really good stuff, I have to wade through a lot of crap.

And with all of the reading and researching I’ve done over the years, I’ve yet to find a reliable, honest, knowledgeable, straight-shooting newsletter, website, or blog about supplements. It seems as though everyone has an agenda, and a lot of the recommendations/opinions are heavily persuaded by the almighty dollar (sometimes very discreetly). Even some of the strength coaches that I highly respect occasionally sprinkle their articles with supplement propaganda. So last weekend, I decided enough is enough. Muscle Geeks will have the first newsletter dedicated to calling out the BS in the supplement industry.

Remember the “mystery” experiments in chemistry lab? You’d set up your Bunson burner, test tubes, funnels, and filters. You’d start the experiment with a huge beaker of some chemical mixture dissolved in a solution, and it was your job to determine what the main chemical was. Three hours and $200 worth of broken test tubes later, you’d have one small grain of some kind of purified substance left to run a test on. In a sense, that’s what this newsletter will be: a science experiment that separates the good from the bad, the pure from the BS, and the science from the marketing.

So, starting this Sunday, the first “Weekly Supplement BS Report” will be published.

-Doc

My creatine is better than your creatine

August 10, 2009 by admin  
Filed under Supplement Cons, Uncategorized

“Creatine has become one of the most extensively studied and scientifically validated nutritional ergogenic aids for athletes.”

-Journal of the International Society of Sports Nutrition, 2007

Without a doubt, creatine is the most effective supplement on the market today. And because of that, it’s also one of the most successful supplements. Its popularity has led to an entire lineage of 2nd, 3rd, and 4th generation creatines. Now the question still remains: are the new generation creatines really that much better than plain old creatine monohydrate? Better, yet, are they worth the price tag? By the time you finish reading this article, you’ll know the answer to both of those questions, plus :

-If I’m a non-responder to regular creatine monohydrate, will one of the new creatine supplements work?

-How much creatine do I really need to take and when should I take it?

-What kind of training works best with creatine?

-Do I need to take anything else with creatine to make it more effective?

-Should I cycle on/off of creatine?

Let’s start from the beginning.

How will it make me bigger?

What is the fundamental principle behind getting bigger? You guessed right. The progressive overload principle: the constant increase in stress placed upon your body during training. More simply stated, increasing the number of reps, sets, or weights from workout to workout. If you benched 225 pounds for 5 sets of 5 reps this week, you better either increase the reps, sets, or weight next week. If you don’t, you’re not giving your body a reason to adapt and grow bigger and stronger.

So what does creatine have to do with progressive overload? Your body uses energy (ATP) to lift weights. The more energy you have available, the more work you can do. Your body creates ATP via 3 different pathways: the phosphagen system (creatine), anaerobic glycolysis (carbohydrates without oxygen), and aerobic glycolysis (carbohydrates with oxygen). Depending on the intensity of the exercise and the rate at which ATP is needed, your body will automatically determine which system it will rely on to create ATP. Because weightlifting is usually intense and brief (a set usually doesn’t last more than 30 seconds without rest), your body will primarily rely on the phosphagen system and anaerobic glycolysis because both of these systems are capable of producing ATP quickly. However, the downside is that they both run out of gas relatively quickly too. Your muscles only have so much creatine available to help create energy. And this is where creatine comes into play…

Taking creatine can increase the amount of creatine within your muscles by anywhere from 10-40%(1). That’s an extra 10-40% of energy available to your muscles. With that much extra energy available, instead of lifting 5 reps, you’d be able to lift 6, 7 or even 8 reps now. And whenever you’re increasing the amount of weight or reps, you’re following the progressive load principle, and your muscles are getting bigger and stronger.

And what kind of gains can I expect?

With a nearly 70% success rate2, don’t write off your results as a placebo-like effect. Expect an extra 5-15% increase in strength and performance.(2) And when that 5-15% is converted to pounds, it always makes a max effort look that much better.

Better yet, studies have also shown that you can expect to double the amount of muscle mass you’d expect to gain if you weren’t using creatine.(3) Pretty impressive.

How much and when?

When creatine first hit the market in the 90s, the standard dosing protocol was 20 grams in divided doses for 3-5 days followed by 5-10 grams daily thereafter. That’s still an effective dosing regimen. However, recently coaches have been recommending a slightly more individualized dosing regimen similar to how most prescription antibiotics are dosed. They suggest 0.3mg/kg/day for 3-5 days, followed by 3-5 grams daily thereafter. So for a 200lb male, that’d be around 27 grams (in divided doses) of creatine for the initial 3-5 days, followed by 3-5 grams daily thereafter.

The new dosing regimen makes sense. Creatine is stored primarily within your muscles. The more muscle you have, the more creatine storage capacity you have. A 120lb beginner should not be using the same amount of creatine as a 260lb professional bodybuilder. The difference in muscle mass is huge. It’s like the difference in the amount of water used to fill up a water balloon and a pool. Also, if we calculate our daily protein intake in a similar fashion, why shouldn’t that apply to creatine? But the real question is: does it matter? Yes and no. Will, in the end, both dosing regimens give you the same result? Yes. However, the original dosing regimen is just going to take a little longer so the results will not seem as dramatic.

As far as when to take it, that’s a little more un-scientific. In fact, it’s largely my opinion. During the initial 3-5 days, I take 5 grams in the morning, at lunch, at dinner, and before bed. I always try to take it with my meals because there have been several studies that have shown that carbohydrates and protein actually increase the amount of creatine that gets inside your muscles. After the initial loading dose, I take 3 grams before my workout, and 3 grams immediately after. By taking 3 grams 30-45 minutes before my workout, I get assurance that my muscles are going to have a supply of creatine waiting for them. After my workout, my muscles are usually begging for nutrients. With the proper postworkout nutrition, I can get more creatine back into my muscles than at any other time.

I also recommend not cycling creatine. The theory behind cycling makes sense. For creatine to enter the cell, it must move through a transporter that scientists have conveniently named the creatine transporter. Scientists theorized that if the transporter is constantly bombarded with creatine, it will develop a level of resistance to the suppement, similar to how Type II diabetes begins. When it develops this resistance, creatine becomes less effective. To circumvent this, they recommended avoiding creatine intake for “x” amount of days to refresh the creatine transporter. There was one study (that I know of) that supported this theory. However, it was done in rats, and the dosage, if extrapolated to a human dosage, would have been astronomical. There’s just never been any human data supporting this theory, and it’s fallen out of favor within the last 5 years. Bottom line: don’t cycle your creatine.

Will plain old creatine monohydrate work for me?

A resounding YES!

There are a few individuals that just don’t respond to creatine monohydrate. It’s because of these individuals that supplement companies create a new creatine every 3 months or so. These companies then try to convince the entire creatine market that their new version of creatine is vastly superior to every other version available. Their marketing ploy, “Our creatine has helped John Doe, who has never got any results from regular creatine, to increase his bench by 50 lbs. Just think what it can do for you if you got results from the less potent creatine monohydrate.” Simply not true. To date, I have yet to see one study that convincingly finds one of the newer forms of creatine is superior to creatine monohydrate.

So let’s take a look at some of the newer forms.

Creatine ethyl ester

Good in theory, poor in results. The creators attempted to attach an ethyl ester to the creatine molecule to make it more fat soluble. Because cells are surrounded by fatty membrane, they hoped by increasing its fat solubility, the CEE would bypass the creatine transporter and move directly into the cell. Thus, in case the creatine transporter was the problem, CEE wouldn’t be affected.

However, not only does it taste horrible, but it also has never been shown to be superior to creatine monohydrate. In fact, there was a study published in the Journal of the International Society of Sports Nutrition entitled “The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels.” that concluded, “When compared to creatine monohydrate, creatine ethyl ester was not as effective at increasing serum and muscle creatine levels or in improving body composition, muscle mass, strength, and power.”

Pass on CEE. Your wallet and your taste buds will thank you for it.

Creatine pyruvate/citrate

This time the supplement manufacturers took a slightly different approach. By combining pyruvate or citrate with creatine, not only are you adding an acid to base with hopes of increasing its bioavailability, but you’re also adding another possible performance-enhancing supplement to the mix. Both pyruvate and citrate have had mixed reviews regarding improvements in endurance training.

However, even though there’s a little more evidence supporting these two creatine combinations, overall the jury is still inconclusive. For every positive study, there’s a negative study refuting the possible benefits. Are they worth the price tag? Absolutely not. Once again, there has yet to be a study that convincingly demonstrates their superiority over creatine monohydrate.

Creatine with sodium

This is probably the most interesting creatine combination. The creatine transporter that was mentioned earlier is thought to be dependent on a sodium/chloride pump. Some scientists believe that creatine requires two molecules of sodium and one molecule of chloride to enter the cell. So by adding sodium to creatine, the sodium concentration gradiant is increased (more on the outside than the inside, think teeter-totter), and the cell is “tricked” into accepting creatine. The only problem is that we haven’t had any definitive real-world feedback. Even though it makes sense from a scientific standpoint, so does CEE. That doesn’t mean it’s going to work in the real-world. As of now, it’s not worth the money. Until a study is done and it concludes creatine combined with sodium is superior to creatine monohydrate, pass on it.

Effervescent creatine and serum creatine

Junk. Don’t even think about it.

Creatine with carbohydrates

Not only is this the most effective means for getting more creatine into the muscle, but it’s also the cheapest. The carbohydrates cause an insulin surge in your bloodstream. Because insulin is highly anabolic, it acts like a key and makes the cell more receptive to outside influences. The more receptive a cell is, the more creatine that can enter. Pretty simple.

Side note: This is also why it’s extremely important to have carbohydrates in your postworkout shake. Not only do they replenish your glycogen stores, but they also cause a surge of a highly anabolic hormone, insulin. That’s an extremely good thing, especially if you’re in a state of catabolism.

A study entitled “Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans.” in the American Journal of Physiology showed that by adding 93 grams of a simple carbohydrate solution, you can increase total creatine concentration by 60% compared to regular creatine supplementation. However, the question still remains though: Does the increase in total muscle creatine result in an increase in performance? That question has yet to be answered definitively. In my opinion, it can never hurt to have too much creatine within the muscle. Plus, for the cost, it doesn’t hurt to try. A 4 pound bag of dextrose shouldn’t cost more than a couple of bucks.

Creatine with protein and carbohydrates

This is my personal favorite. The same theory that applied to creatine and carbohydrates also applies here. However, we’ve added another potential anabolic agent to the mix: protein. Now not only does the surge of insulin from the carbohydrates help more creatine enter the cell, but hopefully more amino acids will also follow suit. And don’t worry if you think the amino acids will prevent additional creatine from entering the cell. A clinical trial entitled “Protein- and carbohydrate-induced augmentation of whole body creatine retention in humans.” found in the Journal of Applied Physiology found that the mixture of protein and carbohydrates was just as effective as carbohydrates alone in improving creatine retention.

So not only does mixing all three make it more convenient, but it appears as though it may also make it more effective. Plus, it’s extremely cheap.

Side note: If you’re dieting and concerned with the extra calories from the carbohydrates, don’t fret too much. Taking creatine by itself will work just fine.

Creatine with supplements that improve insulin sensitivity

Unless you have insulin resistance, I don’t really see the cost-effectiveness of this combination. If you’re lifting weights, on a decent nutrition plan, and taking fish oil, your insulin sensitivity is not going to be the weak link in the creatine equation. Until there’s more evidence, save your money.

If creatine monohydrate doesn’t work for me, will one of the newer ones?

This is probably going to be the most controversial segment of this article. There’s going to be several supplement manufacturers that won’t be too pleased with my answer. First let’s look at why you might not be responding to creatine. Hopefully, before I give you my answer, you will have already formed your own.

Even though 70% of the clinical trials show a positive benefit to creatine use, there are still 30% of studies that show no benefit. One study actually estimated that out of 10 users, between 2 and 3 users will not benefit from creatine supplementation. (4) Why? Scientists have yet to pinpoint the exact cause. However, they have developed several theories. The most prominent theory involves a decrease in activity of the creatine transporter. Even though they haven’t been able to explain specifically the cause of the decrease in activity, they have determined a profile of a responder. It includes the 4 following characteristics:

1) Have a lower initial concentration of creatine within the muscle
2) Have a greater number of type II muscle fibers
3) Have more fiber cross sectional area
4) Have more fat-free mass, aka muscle

All 4 characteristics make sense.

So, if the new creatine product doesn’t improve one of those 4 characteristics, it’s probably not going to be of much help to you. By the way, none of them do. None of them are going to give you bigger muscles. None of them are going to give you more Type II muscle fibers. And none of them are going to decrease the amount of creatine you already have in your muscles. If the creatine transpoter theory holds true, you’re probably SOL.

Carbohydrates are going to be your only choice. In the future, maybe a creatine and sodium combination may help, but that’s a big maybe.

Cliff notes:
- If you’re a non-responder, wait until a product clearly demonstrates that it increases total muscle creatine content COMPARED to regular creatine monohydrate. Thus far, none have.
- If you’re a responder, don’t bother wasting money on new creatines. Stick with creatine monohydrate. Save your money and use it on more protein, beta alanine, or fish oil.

Hopefully, this article has answered a lot of questions that other “experts” have left unanswered or even worse, let the supplement manufacturers answer. Remember, cost-effectiveness should be your primary concern when buying supplements. If it doesn’t produce quantifiable results, don’t buy it. There’s too much junk on the market. This industry has been built on clever marketing, not quantifiable results. Shop smart!

P.S.
I was going to finish with a comparison chart between the products. However, the manufacturers have conveniently made it almost impossible to determine how much creatine is in their product. So instead, I’ll leave you with this:

BSN Cell Mass
Muscle Geek Price: $33.19
At most, a serving has 4 grams of creatine in it.
If using the manufacturers’ directions, 1 bottle will last 25 days.

Dymatize Creatine 1100 grams
Muscle Geek Price: $17.29
5 grams per serving
For a 200lb athlete, using the updated dosing guidelines, a bottle will last ~165 days

Cost-effectiveness

6.6 bottles of CellMass for a total cost of $199.14 = 1 bottle of 1100 grams of Dymatize creatine at a cost of $17.29

Is CellMass really $180 better? Better yet, would that $180 be better spent on our Dymatize protein special of 25 lbs for ~$180? I’d be willing to bet the second option would lead to much better results. In fact, I’d say you’ll probably triple or quadruple your results if you went with the second option. That’s cost-effectiveness!

-Doc

1. Kreider RB: Creatine in Sports. In Essentials of Sport Nutrition &
Supplements Edited by: Antonio J, Kalman D, Stout J, et al. Humana
Press Inc., Totowa, NJ; 2007 in press

2. Kreider RB: Effects of creatine supplementation on performance
and training adaptations. Mol Cell Biochem 2003, 244:89-94.

3. Noonan D, Berg K, Latin RW, Wagner JC, Reimers K: Effects of varying
dosages of oral creatine relative to fat free body mass on
strength and body composition. J Strength Cond Res 1998,
12:104-108.
4. Greenhaff PL, Bodin K, Soderlunk K, et al. Effect of oral creatine supplementation on skeletal muscle phopshocreatine resynthesis. Am J Physiol. 1994:266:E745-E730.

Muscle Geeks: Changing business one geek at a time

July 12, 2009 by admin  
Filed under Muscle Geek News

Before you invest in any business, it’s always nice to know its plans for the future. In fact, most investors won’t pay a dime until they’ve scrutinized the entire business plan. They’re looking for a big return on investment. Because you invest in Muscle Geeks when you purchase a membership, you should be no different. I’m sure you what to know, “What’s in it for me?”.

Let’s take a journey into the future, the very near future!

You just finished wreaking havoc on your chest during a grueling 45 minute workout. Every single fiber in your pectoral muscles is screaming bloody murder, and soreness is quickly ensuing. It’s the good soreness though. The kind that objectively reaffirms that you just kicked your own ass, and you’re sure your chest will be an inch fuller by next week. On your way out of the gym, you hear a couple of guys raving about a new supplement called NO Plasmacore from Muscle Asylum Project. You hear one of them say, “The pumps were insane. I couldn’t even finish my last set of bicep curls. My arms were so juiced I could only curl an inch or two.” Damn, now you start second-guessing your workout. It was great, and you really killed your chest, but what if you were using that nitrous product. You would have annihilated your pecs so much that you wouldn’t be able to take your own shirt off for two days because of the pump. It would have been one of those workouts that forced you to install a couple more mirrors throughout the house just so you can get a peak of those new pecs that are quickly starting to resemble the Rocky Mountains.

An Amazon-like experience

As soon as you finish your postworkout shake, you go directly to your computer, and log onto Muscle Geeks’ new website. You punch in NO Plasmacore, and quickly up pops an Amazon.com-like description of it. First thing on your agenda: the price. Lower than what you thought. Only $0.99 over our cost, and $10 below the next nearest competitor. How do you know that? Because the new website has the top 5 competitor’s prices right next to the Muscle Geek price. Now you don’t have to waste valuable time price shopping. And the best part? You get the lowest price, even if it’s not Muscle Geeks’ price (even though 99 times out of 100 it will be). That’s right. We’ll order it from our competitor, and ship it directly to you. Hassle-free!
Time spent: 10 seconds

Technical medical jargon no more
Thus far, it’s passed the price test. Now, you want to see what makes it so special. You click on the ingredients’ link that’s directly below a crystal clear image of the product. Up pops the manufacturer’s label. 50 servings? Not bad. There’s a ton of ingredients, half of them you can barely pronounce. Ester-this, methyl-that. You need 6 years of pharmacy school just to decipher the names. No worries. Our pharmacist has already done it. Next to each ingredient name is a simple, straightforward, no-medical jargon explanation of what the ingredient is and does. Quick and easy.

Time spent: 30 seconds

Does it mix
Everything looks good. Now you’re worried about the taste and mix-ability of it. With so many ingredients, it can’t possibly mix easily, let alone taste good. Lucky for you, to the right of the product picture is a youtube video entitled “Does it mix like concrete?”. You click on it, and you’re quickly taken into the Muscle Geeks’ lab that’s attached to our main warehouse. You see three men in white jackets, a blender, a spoon, a shaker bottle, 2 cups, and a bottle of NO Plasmacore. The first man takes a serving of NO Plasmacore and mixes it into 12 ounces of water with a spoon. The second man takes a serving and mixes in 12 ounces of water in a blender. And the third man takes a serving and mixes in Gatorade in the shaker cup. After 20 seconds of mixing, the camera zooms in on each end product. The results: Spoon test: Failed, large chunks that can easily get stuck in your throat. Shaker cup test: Passed, small chunks, but you can easily swallow those with no problems. The blender test: Passed with flying colors. No chunks, and it’s almost a little transparent.

Time spent: 30 seconds

Does it taste like crap?
Now you click on the video directly underneath the mixing video entitled, “Does it taste like crap?”. Once again, you’re taken into the Muscle Geeks’ lab. You see three men in white jackets blindfolded, 9 cups, a pitcher of water, a jug of Gatorade, and a box of Crystal Light pink lemonade mixes. An attractive female lab assistant pours each of the liquids into each cup. She then takes a serving of NO Plasmacore and mixes it in each cup. Each man takes three drinks from each cup. The results: Water test: 5 thumbs down, 1 thumb up. Gatorade test: 3 thumbs up, three thumbs down. The Crystal Light test: 5 thumbs up, 1 thumb down.

Time spent: 20 seconds

Nitrous Comparison
Now you’re really interested. However, you still have a little doubt. What if there’s a better nitrous product out there. Is it really better than NO-Xlpode? No worries. Directly underneath the youtube videos, you see a bar graph that compares the top nitrous products. NO Plasmacore is on it, as is NO-Xlpode, Superpump 250, and Nitrotech. Lucky for you, a lot of Muscle Geek members have already voted. NO Plasmacore gets a 3.5, placing it second behind NO-Xlpode.

Time spent: 10 seconds

Detailed Reviews
One last thing. You want to see some detailed customer reviews. No worries. Directly underneath the product picture, you see NO Plasmacore has 103 reviews. You quickly notice these aren’t your typical reviews. The detailed feedback rival that of tripadvisor.com. Why? Because our reviews are rated by our members. The more helpful the review, the better the rating, and the closer to the top. Thus, you won’t have to spend an hour wading through 30 reviews that say. “It’s awesome man.” The ones that will help you make your decision the most are at the top.

Time spent: 60 seconds

The purchase
Now you’re ready. You’ve only spent 2 minutes and forty seconds on the site, but it feels as though you’ve already taken NO Plasmacore because you know so much about it. You know the price, the ingredients, how well it mixes, how well it tastes, if it’s the best product in its category, and have read some great, detailed user feedback all in the time it would have taken you to price shop at your last retailer.

The add-on
However, right before you hit purchase, you see a horizontal section that’s entitled “Other Geeks have also bought this.” Usually, you’re annoyed by that sneaky up-sell tactics that most other retailers use. However, you’re feeling sympathetic today. Hell, you didn’t even know about NO Plasmacore until today. Maybe there’s something else out there that can help. You notice 35% of the Geeks that bought NO Plasmacore also bought ON’s 100% Whey. What the heck? You need some protein anyways. You add it to your cart in one click.

The bill
Let’s add up the bill. NO Plasmacore: $0.99 over our cost, $10 below the next nearest competitor. ON 100% Whey 5 lbs: $0.99 over our cost, $8 below the next nearest competitor. Shipping: $6. Dang, that’s only $8.98 over our cost, and that includes shipping. You’d pay over that on a single supplement at your previous supplement retailer. It’s almost like owning your own supplement store, but better because you don’t have to worry about employees, rent, taxes, or inventory. And you get it all for only $4 per month, less than a price of two waters at your local gym.

And the best part…
Because you worked out at 6 in the morning, you sent your order before noon. The next two days you have off. By your next workout, you’ll have your NO Plasmacore and 100% Whey Protein ready for an intense arm workout. How? Because Muscle Geeks has 6 strategically placed warehouses throughout the U.S. so every order is guaranteed to arrive within 3 days, with most orders arriving in 2 days!

Peter Pan, is this make believe?
No, it will soon be a reality. We are committed to this vision. We firmly believe this is the future of business. All of our profits and owners’ salaries are being put right back into Muscle Geeks. No bonuses, no raises, and minimum wage for every Muscle Geek employee until we achieve our goals. Remember, our initial investment in Muscle Geeks was virtually $0. We were already using our website for our gym, our warehouse was connected to our gym, and our employees were already working for our gym (We were way overstaffed). Everything should be profit.

If we had just 5% of bodybuilding.com’s orders, this would already be a reality. It’s not going to take much. 10,000 members may sound like a lot, but when the industry is a $22 billion industry, that’s a drop in the bucket. Think about how many people just at your gym uses supplements. Almost every single member, and your gym is one of hundreds of thousands of gyms across the U.S. That’s a lot of potential Muscle Geek members.

How do we turn this into a reality?
Join now, and promote Muscle Geeks like crazy. We’ll help in every way we can, because just like you, we’ll save money on our supplements as our membership grows. We’ll give you shirts, business cards, flyers, etc. If you need it, we’ll get it to you. We’re getting ready to launch a MMA campaign, and we’re in negotiations with a major fitness center chain. We’re trying everything we can to spread the word, but we need your help. Trust us, word-of-mouth marketing is our best bet. Not only does it cost nothing, but people trust people they know.

Remember, manufacturers’ discounts are based on supplement order volume. The more members we have, the bigger our supplement volume, and the cheaper our prices. Right now, our markup is always going to be only $1.99 over our cost (eventually $0.99), no matter how big the discount is. That’s anywhere from 20-40% below WHOLESALE cost. Thus, our prices will continue to drop. We’ll do our best to negotiate the biggest discounts possible, but we need firepower. And that firepower comes in the form of you, and every other Muscle Geek member. The bigger our buying power, the cheaper the prices.

Did we forget something?

Did we forget about a clever marketing idea? Or how about something that would be a great add-on to our site? Let us know. We depend on the Muscle Geek community for answers, ideas, and recommendations. We don’t have CEOs or a board of directors. We have our members, and that’s it!

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Muscle Geeks: Greatest invention since the telephone

June 24, 2009 by admin  
Filed under Muscle Geek News

Not really. But, the future of our company is eerily similar to the early days of the telephone. See, the telephone’s success was largely dependent on one factor: mass usage. The more people that had a telephone, the more valuable it became. What benefit would it offer you if you’re the only person in the world that had one? Zero! It’d be completely useless to you. You wouldn’t understand/see the real benefit unless everyone (or almost everyone) had one. Only then would it achieve its true potential, the vision that Alexander Graham Bell had for it. The original customers took a risk, and chose that vision over the short-term pitfalls. They saw the light at the end of the tunnel.

Muscle Geeks’ future success will largely be determined in much the same way. Our true vision will not be seen until we have mass usage, 5,000 or more members, which is entirely possible (we’re actually projecting 10,000 members by 2010). The larger our community becomes, the greater our savings will be. Supplement volume dictates manufacturers’ discounts: the more members, the more volume, the bigger the discounts, and the cheaper the prices. 

Side note: Don’t get us wrong. Even with only 100 members, you’ll still save money with Muscle Geeks. Our prices are still among the cheapest on the planet. Plus, we offer the Muscle Geek Guarantee: If you don’t save your initial $65 membership fee within the first 12 months, we’ll refund the $65 and give you another $35 for your hassle.

Don’t settle for the prices you’re paying right now because it’s probably way too much. You’re probably paying an extra 10, 20 or even 30% PER supplement. We need to pool our buying power together so that we don’t have to pay that extra 30%. Muscle Geeks allows us to accomplish that.

Take the following example:
When we started Muscle Geeks with zero members, our BSN discount was 20% off wholesale cost. After almost 100 members, we were able to negotiate a 25% discount for BSN items. If we had 10,000 members, I guarantee we’d be negotiating ~40% discount or more. Look at these numbers:
  • NO-Xlpode with a 20% discount: $34.84
  • NO-Xlpode with current 25% discount: $32.66 (a little over $2 savings)
  • NO-Xlpode with a 40% discount: $26.13.

I dare you to find a supplement retailer that sells NO-Xlpode for $26.13. You probably couldn’t find one that came within $7 of $26.13. That’s our vision: prices so low that makes our members think “those Geeks must be doing something illegal.”

Another side note: Most supplement retailers mark up BSN products very little, even GNC. Because of its popularity, low prices on BSN supplements draws consumers to their store. Then the retailers mark up the other manufacturers to “make up for the loss” on BSN supplements. Wal-Mart does this with their $4 generics. Thus, this example doesn’t fully depict the true Muscle Geek difference. All of our products are $1.99 over cost no matter the manufacturer. We used the NO-Xlpode example because 90% of supplement users are familiar with the average price for a bottle.

That’s why we’re pushing so hard for immediate growth. We won’t reach our true potential with 100, 500, or even 1000 members. We were built to serve 10,000 or even 100,000 members. We strongly believe that Muscle Geeks will change the supplement industry much like the telephone changed communication. This is the first supplement retailer that puts the customer in charge. We’ve completely reversed roles. And that, in turn, results in potentially huge savings. We need you, and we need you now!

What do you have to lose? If you’re buying your supplements somewhere else, we guarantee our prices are just as good. Join Muscle Geeks, and at worst, you’ll be paying the exact same price as you’re paying now. And at best, which is almost guaranteed, if we all join together, our prices will be by far the cheapest on the planet, and we’ll save a ton of money. Plus, you have the Muscle Geek Guarantee so you could actually make $35 if it isn’t what you expected. We’ve tried to eliminate as much risk for you as possible, without impairing our growth. Why buy from a company when you can become part of a company? See the light!

So please, let’s join forces and get the lowest possible prices on supplements we can. Let’s stop wasting money, and start saving money.

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